Ekspert\u00ebt shpresojn\u00eb se k\u00ebrkimi mund t\u00eb \u00e7oj\u00eb n\u00eb zhvillimin e barnave q\u00eb ndalojn\u00eb njer\u00ebzit t\u00eb infektohen Covid ose ta transmetojn\u00eb at\u00eb<\/p>\n
Phoebe Garrett ka ndjekur leksionet universitare pa e kapur Covid-in; ajo madje organizoi nj\u00eb fest\u00eb ku t\u00eb gjith\u00eb rezultuan pozitiv\u00eb m\u00eb pas, p\u00ebrve\u00e7 saj. \u201cUn\u00eb mendoj se jam ekspozuar me vet\u00ebdije rreth kat\u00ebr her\u00eb\u201d, tha 22-vje\u00e7arja nga High Wycombe.<\/p>\n
N\u00eb mars 2021, ajo mori pjes\u00eb n\u00eb prov\u00ebn e par\u00eb sfiduese n\u00eb bot\u00eb p\u00ebr Covid-19, e cila p\u00ebrfshinte pikimin e virusit t\u00eb gjall\u00eb n\u00eb hund\u00eb dhe mbylljen e vrimave t\u00eb hund\u00ebs p\u00ebr disa or\u00eb, n\u00eb nj\u00eb p\u00ebrpjekje t\u00eb q\u00ebllimshme p\u00ebr ta infektuar at\u00eb. Megjithat\u00eb trupi i saj rezistoi.<\/p>\n
\u201cNe kishim raunde t\u00eb shumta testesh dhe metoda t\u00eb ndryshme testimi: tampon\u00ebt e fytit, tampon\u00ebt e hund\u00ebs, lloje t\u00eb tjera tampon\u00ebsh q\u00eb nuk i kisha b\u00ebr\u00eb kurr\u00eb m\u00eb par\u00eb si fitilat e hund\u00ebs \u2013 ku mbani nj\u00eb shtup\u00eb n\u00eb hund\u00eb p\u00ebr nj\u00eb minut\u00eb \u2013 si dhe testet e gjakut, por un\u00eb kurr\u00eb nuk kam zhvilluar simptoma, nuk kam dal\u00eb kurr\u00eb pozitive\u201d, tha Garrett. \u201cMamaja ime ka th\u00ebn\u00eb gjithmon\u00eb se familja jon\u00eb nuk s\u00ebmuret kurr\u00eb me grip dhe un\u00eb kam pyetur veten n\u00ebse ndoshta ka di\u00e7ka pas k\u00ebsaj\u201d.<\/p>\n<\/div>\n
Shumica e njer\u00ebzve njohin dik\u00eb q\u00eb ka rezistuar me kok\u00ebfort\u00ebsi ndaj infektimit me Covid, pavar\u00ebsisht se t\u00eb gjith\u00eb rreth tyre s\u00ebmuren. Se si ata e b\u00ebjn\u00eb k\u00ebt\u00eb mbetet nj\u00eb mister, por shkenc\u00ebtar\u00ebt kan\u00eb nisur t\u00eb gjejn\u00eb disa t\u00eb dh\u00ebna.<\/p>\n
Shpresa \u00ebsht\u00eb se identifikimi i k\u00ebtyre mekanizmave mund t\u00eb \u00e7oj\u00eb n\u00eb zhvillimin e barnave q\u00eb jo vet\u00ebm i mbrojn\u00eb njer\u00ebzit nga infektimi me Covid, por edhe i pengojn\u00eb ata ta kalojn\u00eb at\u00eb.<\/p>\n
Garrett nuk \u00ebsht\u00eb i vetmi pjes\u00ebmarr\u00ebs i prov\u00ebs sfiduese q\u00eb ka shmangur infektimin. Nga 34 q\u00eb u ekspozuan ndaj virusit, 16 nuk arrit\u00ebn t\u00eb zhvillonin nj\u00eb infeksion (t\u00eb p\u00ebrcaktuara si dy teste t\u00eb nj\u00ebpasnj\u00ebshme pozitive PCR) \u2013 megjith\u00ebse rreth gjysma e tyre rezultuan p\u00ebrkoh\u00ebsisht pozitiv\u00eb p\u00ebr nivele t\u00eb ul\u00ebta t\u00eb virusit, shpesh disa dit\u00eb pas ekspozimit.<\/p>\n
Ndoshta, ky ishte nj\u00eb reflektim i sistemit imunitar q\u00eb mbyllte me shpejt\u00ebsi nj\u00eb infeksion embrional. \u201cN\u00eb studimet tona t\u00eb m\u00ebparshme me viruse t\u00eb tjera, ne kemi par\u00eb p\u00ebrgjigje t\u00eb hershme imune n\u00eb hund\u00eb q\u00eb lidhen me rezistenc\u00ebn ndaj infeksionit,\u201d tha profesor Christopher Chiu n\u00eb Imperial College London, i cili drejtoi studimin. \u201cS\u00eb bashku, k\u00ebto gjetje n\u00ebnkuptojn\u00eb se ekziston nj\u00eb luft\u00eb midis virusit dhe prit\u00ebsit, e cila n\u00eb pjes\u00ebmarr\u00ebsit tan\u00eb \u2018t\u00eb painfektuar\u2019 rezulton n\u00eb parandalimin e p\u00ebrhapjes s\u00eb infeksionit\u201d.<\/p>\n
Disa prej tyre gjithashtu raportuan disa simptoma t\u00eb buta, t\u00eb tilla si hund\u00eb e bllokuar, dhimbje fyti, lodhje ose dhimbje koke \u2013 megjith\u00ebse, meqen\u00ebse k\u00ebto ndodhin zakonisht n\u00eb jet\u00ebn e p\u00ebrditshme, ato mund t\u00eb ken\u00eb qen\u00eb t\u00eb palidhura me ekspozimin ndaj virusit.<\/p>\n
\u201cSido t\u00eb jet\u00eb, nivelet e virusit nuk u ngjit\u00ebn aq lart sa t\u00eb shkaktonin nivele t\u00eb dallueshme t\u00eb antitrupave, qelizave T ose faktor\u00ebve inflamator\u00eb n\u00eb gjak q\u00eb zakonisht shoq\u00ebrohen me simptoma\u201d, tha Chiu.<\/p>\n
Studime t\u00eb tjera sugjerojn\u00eb gjithashtu se \u00ebsht\u00eb e mundur ta hiqni qafe Covid-in gjat\u00eb fazave m\u00eb t\u00eb hershme t\u00eb infeksionit, p\u00ebrpara se ai t\u00eb krijoj\u00eb nj\u00eb baz\u00eb t\u00eb duhur. P\u00ebr shembull, gjat\u00eb val\u00ebs s\u00eb par\u00eb t\u00eb pandemis\u00eb, Dr Leo Swadling n\u00eb Kolegjin Universitar t\u00eb Londr\u00ebs dhe koleg\u00ebt monitoruan intensivisht nj\u00eb grup punonj\u00ebsish t\u00eb kujdesit sh\u00ebndet\u00ebsor t\u00eb cil\u00ebt ishin t\u00eb ekspozuar rregullisht ndaj pacient\u00ebve t\u00eb infektuar, por q\u00eb kurr\u00eb nuk rezultuan pozitiv\u00eb ose nuk zhvilluan vet\u00eb antitrupa. Testet e gjakut zbuluan se rreth 15% e tyre kishin qeliza T reaktive kund\u00ebr Sars-CoV-2, plus sh\u00ebnues t\u00eb tjer\u00eb t\u00eb infeksionit viral.<\/p>\n
Ndoshta, qelizat T t\u00eb kujtes\u00ebs nga infeksionet e m\u00ebparshme t\u00eb koronavirusit \u2013 pra ato p\u00ebrgjegj\u00ebse p\u00ebr ftohjet e zakonshme \u2013 reaguan me koronavirusin e ri dhe i mbrojt\u00ebn ata nga Covid.<\/p>\n
T\u00eb kuptuarit se sa shpesh njer\u00ebzit abortojn\u00eb infeksionet e sapolindura Covid n\u00eb epok\u00ebn e Omicron \u00ebsht\u00eb e nd\u00ebrlikuar sepse k\u00ebrkon testime intensive \u2013 p\u00ebr virusin, antitrupat, qelizat T dhe sh\u00ebnuesit e tjer\u00eb t\u00eb infeksionit \u2013 edhe sepse shum\u00eb njer\u00ebz jan\u00eb vaksinuar.<\/p>\n
\u201cKa t\u00eb ngjar\u00eb q\u00eb individ\u00ebt e vaksinuar t\u00eb jen\u00eb t\u00eb ekspozuar ndaj virusit dhe t\u00eb bllokojn\u00eb replikimin viral dhe infeksionin m\u00eb shpesh t\u00eb zbuluesh\u00ebm\u201d, tha Swadling.<\/p>\n
Nuk ka gjithashtu asnj\u00eb test t\u00eb disponuesh\u00ebm n\u00eb treg q\u00eb mund t\u00eb b\u00ebj\u00eb dallimin midis imunitetit t\u00eb shkaktuar nga vaksinimi dhe varianteve t\u00eb ndryshme \u2013 k\u00ebshtu q\u00eb n\u00ebse nj\u00eb person nuk ka rezultuar pozitiv s\u00eb fundmi, \u00ebsht\u00eb pothuajse e pamundur t\u00eb dihet n\u00ebse ai ka qen\u00eb i ekspozuar ndaj Omicron apo jo.<\/p>\n
Koronaviruset sezonale mund t\u00eb mos jen\u00eb burimi i vet\u00ebm i p\u00ebrgjigjeve imune nd\u00ebr-mbrojt\u00ebse. Prof. Cecilia S\u00f6derberg-Naucl\u00e9r, nj\u00eb imunologe n\u00eb Institutin Karolinska n\u00eb Stokholm, filloi t\u00eb hetoj\u00eb k\u00ebt\u00eb mund\u00ebsi, pasi Suedia shmangi mbingarkes\u00ebn nga rastet gjat\u00eb val\u00ebs s\u00eb par\u00eb t\u00eb pandemis\u00eb, pavar\u00ebsisht qasjes s\u00eb saj t\u00eb leht\u00eb ndaj kufizimeve. Modelimi matematik nga kolegu i saj, Marcus Carlsson n\u00eb Universitetin e Lundit, sugjeron se ky model i infeksioneve mund t\u00eb shpjegohej vet\u00ebm n\u00ebse nj\u00eb pjes\u00eb e madhe e njer\u00ebzve kishin nj\u00eb lloj imuniteti mbrojt\u00ebs.<\/p>\n
Ekipi i saj kontrolloi bazat e t\u00eb dh\u00ebnave t\u00eb sekuencave t\u00eb proteinave nga viruset ekzistuese, duke gjuajtur p\u00ebr segmente t\u00eb vogla (peptide) q\u00eb ngjasojn\u00eb me ato nga koronavirusi i ri, me t\u00eb cil\u00ebt antitrupat kishin t\u00eb ngjar\u00eb t\u00eb lidheshin. Kur ata identifikuan nj\u00eb peptid me gjasht\u00eb aminoacide n\u00eb nj\u00eb protein\u00eb nga gripi H1N1 q\u00eb p\u00ebrputhej me nj\u00eb pjes\u00eb thelb\u00ebsore t\u00eb protein\u00ebs s\u00eb maj\u00ebs s\u00eb koronavirusit, \u201cp\u00ebr pak sa nuk rash\u00eb nga karrigia\u201d, tha S\u00f6derberg-Naucl\u00e9r.<\/p>\n
Q\u00eb at\u00ebher\u00eb ata kan\u00eb zbuluar antitrupa ndaj k\u00ebtij peptidi n\u00eb afro 68% t\u00eb dhuruesve t\u00eb gjakut nga Stokholmi. Hulumtimi, i cili ende nuk \u00ebsht\u00eb rishikuar nga koleg\u00ebt, mund t\u00eb sugjeroj\u00eb se p\u00ebrgjigjet imune t\u00eb shkaktuara nga gripi H1N1 \u2013 i cili ishte p\u00ebrgjegj\u00ebs p\u00ebr pandemin\u00eb e gripit t\u00eb derrit 2009-10 \u2013 dhe shtamet e m\u00ebvonshme t\u00eb lidhura ndoshta, mund t\u2019i pajisin njer\u00ebzit me mbrojtje t\u00eb pjesshme, por jo t\u00eb plota kund\u00ebr Covid-19. \u201cAi siguron nj\u00eb jast\u00ebk, por nuk do t\u2019ju mbroj\u00eb n\u00ebse nj\u00eb person i infektuar kollitet n\u00eb fytyr\u00ebn tuaj\u201d, tha S\u00f6derberg-Naucl\u00e9r.<\/p>\n
Nj\u00eb pjes\u00eb e vog\u00ebl e njer\u00ebzve madje mund t\u00eb jen\u00eb gjenetikisht rezistent\u00eb ndaj Covid-19. N\u00eb tetor, nj\u00eb konsorcium nd\u00ebrkomb\u00ebtar studiuesish nisi nj\u00eb gjueti globale p\u00ebr t\u00eb gjetur disa prej tyre, me shpres\u00ebn p\u00ebr t\u00eb identifikuar gjenet mbrojt\u00ebse.<\/p>\n
\u201cNe nuk po k\u00ebrkojm\u00eb p\u00ebr variante t\u00eb zakonshme t\u00eb gjeneve q\u00eb ofrojn\u00eb mbrojtje modeste kund\u00ebr infeksionit, ajo q\u00eb ne po k\u00ebrkojm\u00eb jan\u00eb variante gjenesh potencialisht shum\u00eb t\u00eb rralla q\u00eb mbrojn\u00eb plot\u00ebsisht dik\u00eb kund\u00ebr infeksionit\u201d, tha Prof Andr\u00e1s Spaan n\u00eb Universitetin Rockefeller n\u00eb Nju Jork, i cili drejton hulumtimin.<\/p>\n
Ata jan\u00eb ve\u00e7an\u00ebrisht t\u00eb interesuar p\u00ebr njer\u00ebzit q\u00eb ndanin nj\u00eb sht\u00ebpi dhe shtrat me nj\u00eb person t\u00eb infektuar dhe shmangnin vet\u00eb infeksionin. \u201cP\u00ebr shembull, nj\u00eb dit\u00eb m\u00eb par\u00eb po flisja me nj\u00eb zonj\u00eb t\u00eb moshuar nga Holanda, e cila u kujdes p\u00ebr burrin e saj gjat\u00eb val\u00ebs s\u00eb par\u00eb. Burri p\u00ebrfundimisht u shtrua n\u00eb spital, por ajo kaloi nj\u00eb jav\u00eb para se t\u00eb kujdesej p\u00ebr t\u00eb, duke ndar\u00eb t\u00eb nj\u00ebjt\u00ebn dhom\u00eb dhe pa maska p\u00ebr fytyr\u00ebn\u201d, tha Spaan. \u201cNe nuk mund t\u00eb shpjegojm\u00eb pse ajo nuk u infektua\u201d.<\/p>\n
Nj\u00eb rezistenc\u00eb e till\u00eb dihet se ekziston p\u00ebr s\u00ebmundje t\u00eb tjera, duke p\u00ebrfshir\u00eb HIV-in, malarien dhe norovirusin. N\u00eb k\u00ebto raste, nj\u00eb defekt gjenetik do t\u00eb thot\u00eb se disa njer\u00ebzve u mungon nj\u00eb receptor i p\u00ebrdorur nga patogjeni p\u00ebr t\u00eb hyr\u00eb n\u00eb qeliza, k\u00ebshtu q\u00eb ata nuk mund t\u00eb infektohen. \u201cMund t\u00eb ndodh\u00eb q\u00eb, n\u00eb disa individ\u00eb, t\u00eb ket\u00eb nj\u00eb defekt t\u00eb till\u00eb n\u00eb nj\u00eb receptor t\u00eb p\u00ebrdorur nga Sars-CoV-2\u201d, tha Spaan.<\/p>\n
Identifikimi i gjeneve t\u00eb tilla mund t\u00eb \u00e7oj\u00eb n\u00eb zhvillimin e trajtimeve t\u00eb reja p\u00ebr Covid-19, n\u00eb t\u00eb nj\u00ebjt\u00ebn m\u00ebnyr\u00eb q\u00eb identifikimi i defekteve t\u00eb receptorit CCR5 te njer\u00ebzit rezistent ndaj HIV-it ka \u00e7uar n\u00eb m\u00ebnyra t\u00eb reja t\u00eb trajtimit t\u00eb HIV-it.<\/p>\n
Spaan mendon se nuk ka gjasa q\u00eb shumica e atyre q\u00eb kan\u00eb shmangur Covid-in t\u00eb jen\u00eb gjenetikisht rezistent\u00eb, edhe n\u00ebse kan\u00eb nj\u00eb mbrojtje t\u00eb pjesshme imune. Kjo do t\u00eb thot\u00eb se nuk ka asnj\u00eb garanci se ata nuk do t\u00eb infektohen p\u00ebrfundimisht \u2013 si\u00e7 zbuloi Garrett n\u00eb fund t\u00eb janarit. Pasi iu shmang virusit p\u00ebr gati dy vjet, ajo u trondit kur nj\u00eb test rutin\u00eb tregoi nj\u00eb vij\u00eb t\u00eb dyt\u00eb t\u00eb kuqe ogurzez\u00eb. Menj\u00ebher\u00eb pas k\u00ebsaj, ajo zhvilloi simptoma t\u00eb buta Covid, por q\u00eb at\u00ebher\u00eb \u00ebsht\u00eb rikuperuar.<\/p>\n
Ironia \u00ebsht\u00eb se, pasi ka shmangur infektimin me Covid nga familja e ngusht\u00eb, miqt\u00eb dhe n\u00eb nj\u00eb laborator mjek\u00ebsor t\u00eb specializuar, ndoshta ka qen\u00eb nj\u00eb i huaj farefisnor q\u00eb e ka infektuar at\u00eb. \u201cNuk e kam iden\u00eb nga e kam marr\u00eb; mund t\u00eb ket\u00eb qen\u00eb dikush n\u00eb korin tim lokal, ose ndoshta nga palestra,\u201d tha ajo.<\/p>\n
<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"
Ekspert\u00ebt shpresojn\u00eb se k\u00ebrkimi mund t\u00eb \u00e7oj\u00eb n\u00eb zhvillimin e barnave q\u00eb ndalojn\u00eb njer\u00ebzit t\u00eb infektohen Covid ose ta transmetojn\u00eb at\u00eb Phoebe Garrett ka ndjekur leksionet universitare pa e kapur Covid-in; ajo madje organizoi nj\u00eb fest\u00eb ku t\u00eb gjith\u00eb rezultuan pozitiv\u00eb m\u00eb pas, p\u00ebrve\u00e7 saj. \u201cUn\u00eb mendoj se jam ekspozuar me vet\u00ebdije rreth kat\u00ebr her\u00eb\u201d, […]<\/p>\n","protected":false},"author":5,"featured_media":22369,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7652,7521,6332],"tags":[],"class_list":{"0":"post-44309","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-shendetesi","8":"category-shkence","9":"category-te-fundit"},"_links":{"self":[{"href":"https:\/\/jugulajm.net\/index.php?rest_route=\/wp\/v2\/posts\/44309","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/jugulajm.net\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jugulajm.net\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jugulajm.net\/index.php?rest_route=\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/jugulajm.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=44309"}],"version-history":[{"count":0,"href":"https:\/\/jugulajm.net\/index.php?rest_route=\/wp\/v2\/posts\/44309\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/jugulajm.net\/index.php?rest_route=\/"}],"wp:attachment":[{"href":"https:\/\/jugulajm.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=44309"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jugulajm.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=44309"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jugulajm.net\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=44309"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}